The Colorado Trust's original endowment of $191 million was received from the sale of the PSL Healthcare Corporation in 1985. At the end of 2019, The Colorado Trust had assets of more than $525 million.

As a perpetual endowment, The Colorado Trust's investment objective is to make qualifying distributions of grants plus expenses equal to 5% of the endowment each year while maintaining and increasing its real value in perpetuity.

From its inception through 2019, The Colorado Trust has provided more than $563 million in charitable support to grantees across Colorado, including $17.4 million in 2019 alone.